Associate Director (Flow Cytometry) at AstraZeneca

Posted in Other 5 days ago.

Location: Gaithersburg, Maryland





Job Description:

Associate Director (Flow Cytometry)


At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We do this with the upmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people's exceptional skills with those of people from all over the globe. As a part of our Dynamic Omics team, you'll play a pivotal role in channelling our scientific capabilities to make a positive impact on changing patients' lives.



Summary of the Group


The Flow Cytometry group is part of Dynamic Omics/ Centre for Genomics Research (CGR) and Discovery Sciences within AstraZeneca, and works across all therapeutic areas: Oncology, Cardiovascular, Renal and Metabolism (CVRM), Respiratory and Immunology (R&I), Vaccines and Immunotherapies (V&I), Neurosciences, and Rare Diseases. The team supports over 500 scientists globally and delivers key data to projects across all phases of the drug discovery and development, and we work with all modalities from small molecules to biologics. The Flow Cytometry Center of Excellence is among the leading flow cytometry organizations worldwide (as recently recognized by the International Society for Advancement of Cytometry), equipped with state-of-the-art instrumentation and ground breaking technology and expertise.



What you'll do


In this role, you will supervise the operations of the team in Gaithersburg and lead collaborations with multiple therapeutic areas. The successful candidate will have the opportunity to work and grow in a fast-paced environment under the supervision of senior staff members.




  • Oversee the flow cytometry team in Gaithersburg to ensure proper maintenance of the instruments, operations, and training of the new hires.


  • Manage the flow cytometry workflows from experimental design to data analysis of pre-clinical and clinical studies in alignment with the global flow cytometry leadership


  • Establish and maintain relationship with stakeholders to identify development opportunities and align operations with therapeutic areas' needs. Prioritize projects collaborations aligned with AstraZeneca pipeline.


  • Supervise the collaborative efforts with multiple therapeutic areas focusing on innovative immunology/flow cytometry projects and/or automation solutions


  • Summarize data for presentations, reports, and publications with accountability for accuracy. Review and approve flow cytometry data and reports to ensure quality and integrity


  • Demonstrate broad understanding of current and emerging technologies in cellular analyses, with a keen perspective of how novel approaches might fit across each of the supported Therapeutic Areas


  • Demonstrate excellent leadership skills and collaborative and pro-active problem-solving skills to include identifying a problem and taking appropriate actions and knowing when to seek guidance


  • Influence through initiatives, presentations, publications, governing bodies and consortium activities


  • Ensure that work is conducted in a safe and compliant manner; maintain lab documentation, establish SOPs and/or practice in accordance with established SOPs, GLP requirements





Education & Experience Requirements:


Education: MS degree or PhD in Immunology, Bioinformatics, Engineering or a related field


Experience: MS degree and 8+ years of related experience or a PhD degree and 5+ years of related experience



Required Skills & Experience:

  • Experience leading PhD level scientists with significant hands-on experience to operate, maintain, and troubleshoot flow cytometer instrumentations (BD Biosciences, Cytek and Beckman platforms) and cell sorter (BB Biosciences platforms), following best industry practices


  • Lead collaborations and advance projects by standardizing the design of experiments, analysis and interpretation of data from of our preclinical and clinical studies, and summary of experimental results for presentations, review for accuracy and write reports and high-quality/high impact scientific publications


  • Experience with a variety of flow cytometry data analysis and bioinformatic tools, including FlowJo, FCS Express and Omics and/or programming with Python or R


  • Strong multi-tasking, time management, organizational skills and excellent communication skills, both verbal and written


  • Proven ability to lead by example with honesty, integrity, flexibility, creativity, and collaborative spirit thereby building successful teams


  • Ability to handle multiple projects and/or tasks in a fast-paced environment





Desired Skills & Experience



  • Experience with multiomics integration and working with data scientists creating data analysis platforms


  • Extensive experience with setting goals and objectives, motivating and developing scientists and influencing recruitment of successful teams


  • Experience with establishing automated lab processes


  • Experience with Imaging flow and/or microscopy experience




When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and daring world.



Why AstraZeneca?



At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering groundbreaking methods and bringing unexpected teams together. Interested? Come and join our journey.



So, what's next?



Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available, and we hope it's yours.


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
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