Scientist - Bioscience Oncology-Antibody Drug-Conjugates (Lab Based) at AstraZeneca

Posted in Other 15 days ago.

Location: Gaithersburg, Maryland





Job Description:

Scientist - Bioscience Oncology-Antibody Drug-Conjugates (Lab Based)




Gaithersburg, MD



Are you passionate about oncology research and eager to make a significant impact in drug development? If you're driven by the idea of turning scientific ideas into life-changing medicines, then AstraZeneca is the perfect place for you!



Accountabilities:



As a Scientist in our Oncology Research group, you will be responsible for designing, conducting, and analyzing in vitro and in vivo experiments to assess the function of our candidate oncology drugs (antibody drug-conjugates (ADC)). You will also dissect the mechanism of action of these novel therapeutics and review emerging literature and internal data to identify new targets. Your contributions will be instrumental in our target validation activities.



Essential Skills/Experience:



  • Bachelor's degree with 3-5 years' experience or Master's degree with 1+ years' experience in cancer biology or a related field

  • Experience with a range of in vitro skills for the analysis of human tumor cell function (e.g. cell culture, cell signaling bioassays, flow cytometry, high-content imaging, cytotoxicity assays and experimental procedures to assess internalization/trafficking in cancer cell lines.)

  • Experience with ELISA and flow cytometry to investigate binding of ADCs and antibodies to recombinant proteins and cancer cell lines.

  • Works independently with supervision

  • Strong interpersonal and collaboration skills together with evidence of having used these to support problem solving and delivery in a collaborative environment.

  • Good written and verbal communication skills




Desirable Skills/Experience:



  • Knowledge of the drug discovery process and publications in peer-reviewed scientific journals




Why AstraZeneca?



At AstraZeneca, we are united in our vision to eliminate cancer as a cause of death. We are pioneers, making bold moves that transform the way cancer is treated and truly improve patient outcomes. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We believe in growing together and providing a place where everyone can have a voice. We are ambitious and collaborative, optimistic in our ability to be resilient and work together towards a cure.



About Our Gaithersburg Oncology Hub



The Gaithersburg site (https://www.youtube.com/watch?v=GOvxXGjBd1w) employs more than 3,500 experts in our field and is only a short drive from Washington, DC. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.


The Gaithersburg campus offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria, game rooms, community garden and much more.



Are you ready to join our Oncology R&D team and take a crucial inter-disciplinary approach to save patients' lives? Apply now to be part of our mission to eliminate cancer as a cause of death! Apply now to be part of our team!


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
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