Posted in Other 12 days ago.
Location: South San Francisco, California
Innova Solutions is immediately hiring for a Research Associate - III
Position type: Full time
time Contract
Duration: 12 months
Location:
South San Francisco, CA
As a
Research Associate - III
, you will:
Job Description:
The mission of the Investigative Toxicology group is to elucidate the mechanisms underlying toxicities that are observed non-clinically and/or in clinical trials through hypothesis driven research.
This process involves closely collaborating with scientists across the organization to support the overall safety assessment for our novel therapeutics spanning drug discovery through clinical development and marketing.
The group provides fit-for-purpose wet lab-based investigation to address target safety assessment lead optimization and issue mitigation by employing state-of-the-science in vitro and ex vivo approaches. As such we are constantly establishing new platforms and technologies to support a constantly changing portfolio novel modalities and emerging therapeutic area needs.
We are looking for a highly motivated candidate to work in collaboration with other researchers in the Investigative Toxicology lab.
This individual must have experience in cell culture and will be responsible for: culturing and expanding primary cells and cell lines for in vitro screenings treating and performing assays to assess cytotoxicity and metabolic changes of cells capturing cell culture images using confocal and high content imaging.
This individual will be working with cells from a broad range of tissues liver GI vascular ocular and is expected to make detailed observations related to experiments perform analyze data and interpret results.
He/she will contribute with scientific insights and also work in projects related to peer review publications. The individual will also participate in projects related to the development of microfluidics platforms to support toxicity testing for our drug discovery program.
Investigative Toxicology groups goal is to use ex vivo and in vitro tools to assess safety liabilities and mechanisms of toxicity observed pre-clinically to support the entire portfolio spanning discovery through development. This laboratory-based role involves performing qualifying and implementing biological assays and technologies to support the Investigative Toxicology group.
They will also contribute to ongoing efforts to understand the impact of complex-in-vitro models in hazard id and liability assessment.
This is an ideal position for a researcher who is enthusiastic about learning and contributing to projects with a broad range of techniques. As such the position requires excellent communication and collaboration skills a desire to learn about and integrate multiple aspects of drug toxicity and a passion for lab-based research.
In particular a candidate who will be successful in this role will be able to collaborate with subject matter experts to collaboratively design a scope of work and key performance indicators for a research project but then independently drive forward the experimental work including towards identified milestones.
Additionally the success in this role will require flexibility and a willingness to learn new model systems as well as initiative to troubleshoot unexpected experimental results or limitations.
Skills: -
Candidate will provide scientific and technical support to assays and platforms supported or under development by the Investigative Toxicology group by:
Performing experiments involving: immortalized and primary cell culture cell viability assessment ELISAs gene expression analysis high content screening confocal microscopy and flow cytometry. Experience with these methodologies is desirable but not required.
A large portion of the cell culture work conducted will focus on the use of organoid or other complex in-vitro model CIVM systems
Maintaining documentation related to protocol execution and results.
Writing protocols and contributing to final reports as appropriate.
Adhering to departmental SOPs to ensure study integrity and quality.
Conducting experiments with a high level of independence and initiative.
Performing tasks with minimal direct supervision for routine methods and studies commonly employed by the team.
Education: -
Bachelors BS/BA in pharmacology pharmaceutical science biology bioengineering chemistry physiology or related discipline is required Masters MS degree is desirable but not required.
Technical Experience Requirements:
1-3 years of laboratory experience with hypothesis-driven research.
Ability to analyze integrate and present data in a presentation is required.
Experience with immortalized and/or primary cell culture cell viability assessment ELISAs gene expression analysis high content screening confocal microscopy and flow cytometry is highly desired. -Experience with complex in-vitro model systems is highly desired.
Role will Involve:
Sitting or standing for extended periods. - Performing repetitive tasks such as cell culture pipetting and labeling tubes.
Collaboration across the Investigative Toxicology team and with key stakeholders.
Work with potentially hazardous materials including but not limited to: chemotherapeutics biological hazards and human primary cells.
Qualified candidates should APPLY NOW for immediate consideration! Please hit APPLY to provide the required information, and we will be back in touch as soon as possible.
We are currently interviewing to fill this and other similar positions. If this role is not a fit for you, we do offer a referral bonus program for referrals that we successfully place with our clients, subject to program guidelines. ASK ME HOW.
Thank you!
Namrata Gautam
Senior Associate Recruitment
PHONE: (+1) 314-523-1818
EMAIL: Namrata.Gautam@innovasolutions.com
PAY RANGE AND BENEFITS:
Pay Range*: $45- $50 per hour
*Pay range offered to a successful candidate will be based on several factors, including the candidate's education, work experience, work location, specific job duties, certifications, etc.
Benefits: Innova Solutions offers benefits( based on eligibility) that include the following: Medical & pharmacy coverage, Dental/vision insurance, 401(k), Health saving account (HSA) and Flexible spending account (FSA), Life Insurance, Pet Insurance, Short term and Long term Disability, Accident & Critical illness coverage, Pre-paid legal & ID theft protection, Sick time, and other types of paid leaves (as required by law), Employee Assistance Program (EAP).
ABOUT INNOVA SOLUTIONS: Founded in 1998 and headquartered in Atlanta, Georgia, Innova Solutions employs approximately 50,000 professionals worldwide and reports an annual revenue approaching $3 Billion. Through our global delivery centres across North America, Asia, and Europe, we deliver strategic technology and business transformation solutions to our clients, enabling them to operate as leaders within their fields.
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