Scientist, In-Vitro Radioconjugate at AstraZeneca

Posted in Other 13 days ago.

Location: Gaithersburg, Maryland





Job Description:

Do you have a passion for Science? Would you like to apply your expertise to impact a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!


At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being ambitious, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.



About AstraZeneca in Gaithersburg, MD:



Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most ground breaking technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.


The Gaithersburg site offers a variety of amenities to help boost efficiency and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.



Summary of the group



We are seeking a highly motivated Scientist with a consistent track record of scientific excellence to join our radioconjugate (RC) team in the Tumor Targeted Delivery group within AZ Early Oncology Discovery in Gaithersburg, MD, USA. You will be a key member of a team working to develop novel, targeted radioconjugate therapies and advancing them through early pre-clinical development. You will bring your theoretical and practical expertise to support platform and pipeline RC projects, working with a cross-functional team to deliver pre-clinical datasets to support pipeline progression and platform development. You will have the opportunity to present data and represent the team in project team meetings, platform meetings, and other internal forums.



Main Duties & Responsibilities



Working in this laboratory-based position within the Early Oncology Discovery group, you will develop, design, conduct, troubleshoot, and analyze in vitro experiments to validate tool reagents, investigate target biology, and dissect the mechanism of action of these novel cancer therapeutics. You will be expected to support cross-functional teams and work collaboratively with project leaders to ensure the timely generation and dissemination of critical program data. As a highly organized, self-motivated individual with a strong background in laboratory science, you will stay up-to-date with relevant technical and intellectual scientific expertise in tumor biology and cancer modeling and have a genuine passion for this field of research.



Education & Experience Requirements:



  • Bachelor's Degree in a relevant discipline with 5+ years of experience OR a Master's Degree with 2+ years of experience, with a background in a relevant discipline


  • Candidates possessing a Ph.D. degree will not be considered




Required Skills



  • Extensive knowledge of cell biology, molecular biology, and/or biochemistry in the context of cancer biology, with a strong desire for continued learning

  • Experience with routine cell culture, particularly culture of tumor cells

  • Expertise in molecular- and cell-based methodologies, such as cytotoxicity assays, binding and internalization assays, multicolor flow cytometry, fluorescent and live cell microscopy, ELISA, and Western blotting

  • Works independently with minimal supervision to conduct experiments, analyze data, and prepare results for internal and external presentations and regulatory filings

  • Ability to mentor and instruct junior colleagues

  • Excellent communication, presentation, and interpersonal skills and evidence of delivery in a team-oriented, collaborative environment

  • Ensures own work, and work of peers, is compliant with Good Laboratory Practice, Safety, Health, and Environment standards and all other relevant internal AstraZeneca standards and external regulations




Desired Skills



  • Prior experience in the biopharmaceutical industry preferable but not required

  • Experience in molecular cloning and cell line engineering is highly desirable

  • Candidates with experience related to radiation biology, radiochemistry, or radiopharmaceutical therapies would be preferable

  • A proven track record of productivity; contributions to scientific publications in peer-reviewed journals




Why AstraZeneca?



At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering innovative methods and bringing unexpected teams together. Interested? Come and join our journey.



So, what's next!



Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it's yours.



Where can I find out more?



Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/


Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/


Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en


AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
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