Company Description

About Biogen:

At Biogen, our mission is clear - we are pioneers in neuroscience. Biogen discovers, develops, and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. Together, our employees create, commercialize, and manufacture transformative therapies for our patient population.

We at Biogen are committed to building on our culture of inclusion and belonging thatreflectsthe communities where we operate and the patients who we serve.We are focused on strengthening our foundation to advance our overall Diversity, Equity and Inclusion (DE&I) strategy and, most importantly, ensure all our employees feel included.

As an intern or co-op at Biogen, you can expect to be placed on a real project, under the guidance of experienced professionals and subject matter experts who are invested in your career and academic growth. We also ensure that you have plenty of opportunities to build your network, learn more about our organization through weekly lunch and learns led by leaders from across the company, and join us for several fun events.

Job Description

Summary

This application is for a 12-week internship role from June - August 2024. Resume review begins in January 2024.

The downstream drug substance pilot group is responsible for pilot scale execution of downstream unit operations, prior to scaling up to manufacturing. The downstream Pilot group develops and supports the development of several of the unit operations that will make up the final purification process for a biologic therapeutic.

Position Description

As the intern, you will support the development and evaluation of the Repligen TangenX - NovaSep Sius (Hystream 30 kD) Ultrafiltration/Diafiltration (UFDF) filter to reduce COG's in manufacturing downstream processes. You will focus on evaluating TangenX TFF filters as a potential alternative to the Millipore Pellicon Ultracel filters across multiple programs / processes.

Detailed description of role including but not limited to:

• Requesting downstream process intermediate samples from pilot runs and manufacturing batches.




• Conduct and document small scale and pilot scale TFF experiments with a focus on process definition and understanding, assist in experimental design and troubleshooting, and analyze data including process modeling and proof-of-concept analyses.




• Evaluating HySteam TangenX UFDF filter performance and cleanability/membrane regeneration side-by-side with Ultracel filters.

• Authoring a summary report of the data as well as a presentation

Qualifications

Qualifications:

• Knowledge and technical experience in protein purification / biotechnology related filtration development




• Familiarity with the UFDF unit operation is desirable.




• A strong grasp of Excel and higher-level math (calculus) is desirable for this position.




• Excellent verbal and written communication skills, time management and organizational skills.




• Excellency in working with PC based computer systems and relevant applications including Microsoft Word, Excel, and PowerPoint.

To participate in the Biogen Internship Program, students must meet the following eligibility criteria:

• Legal authorization to work in the U.S.




• At least 18 years of age prior to the scheduled start date




• Be currently enrolled in an accredited college or university.

Education

• Exceptional undergraduate student who has completed at least three years of program, or a first year Master's program, with 0-2+ years' experience desired




• Desired majors include: Bio/Chemical Engineering, Biomanufacturing or related field

Location

Research Triangle Park, NC

Additional Information

Why Biogen?

Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients' lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.

At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.