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Job Description
OBJECTIVES
Based in Cambridge, Ma, a researched-based role under general supervision, performing a variety of routine and specialized experimental procedures for the purpose of research in the immuno-oncology field. The scientist will work in a highly matrixed and collaborative environment that relies on the close interactions with the entire IO Biology research team and other functional teams within the organization. A successful candidate will help identify and assess innovative opportunities including those with potential academic and industry collaborators with the goal of developing and executing on the identification of new targets for advancement into the drug discovery portfolio. The candidate will be responsible for working independently to designing well-controlled experiments to support drug target identification and validation studies. Key responsibilities will include independent and collaboratively executing, analyzing and interpreting data from studies designed to understand i) target biology relevant to drug discovery ii) mechanisms of action and iii) proof-of-concept studies. In addition, the candidate will continue to explore and introduce new technological tools and/or methods to further expand the group’s immune-related technical capabilities.
ACCOUNTABILITIES
Partner with teams to design and execute decision enabling preclinical experiments to better understand drug target mechanisms of action and validation for I/O therapeutic application
Independently or collaboratively design, execute and validate a variety of assays to understand targets of interest and characterize different biologic therapeutics for I/O applications
Internalize novel technologies relevant to I/O drug discovery, progressing novel drug target identification and validation
Contribute and implement new ideas with in vitro and in vivo proof of concept studies to enable initiation of new discovery project concepts using scientific theory and technical literature
Extend internal immunology capabilities through external industrial (CRO) and academic collaborations
Assist with planning and execution of specific research procedures, coordinating schedules of experiments and procedures (~75% of time in the laboratory).
Compile data from complex experiments, execute analysis and communicate findings through presentation format
Prepare and presents comprehensive technical or project reports and formal presentations / posters to full range of internal/external audiences
DIMENSIONS AND ASPECTS
Technical/Functional (Line) Expertise
Demonstrates theoretical knowledge of discipline
Keeps current with emerging trends in discipline
Leadership(
Influences team and decision making
May assist in training junior scientist in assay development or other necessary experimental procedures
Decision-making and Autonomy
Independently manages own workload and expectations
Scientifically independent
Interaction
Conducts scientific presentations to internal audiences
Engages in collaborations with internal cross-functional teams.
Engages in a collaborations with external researchers at other companies or academia
Innovation
Receives high level instructions on all work, determines methods on new assignments, works closely with manager, may manage junior staff
EDUCATION, BEHAVIORAL COMPETENCIES AND SKILLS:
PhD or equivalent in immunology or biology-related field or
MS with 6+ years experience, or
BS with 8+ years experience
Demonstrates thorough knowledge of immunological principles and concepts including prior hands-on-experience carrying out data acquisition, analysis and interpretation of molecular or cell-based assays and in vivo experiments
Extensive experience and independence with multiplexing immune profiling platforms (multi-dimension Flow cytometry, Luminex, MSD).
Ability to independently plan, execute and interpret scientific experiments or research aims.
Ability to work and drive decision-making within a multi-disciplinary, multi-regional, matrixed team.
Self-driven and proven ability to learn new techniques and tackle “new” science.
Excellent communication and interpersonal skills, diplomacy and positive influencing abilities.
Effective time and project management skills.
Independently manages workload and expectations.
Scientifically independent.
Right attitude (agile, curious, open-minded, “can-do” mindset)
WHAT TAKEDA CAN OFFER YOU:
401(k) with company match and Annual Retirement Contribution Plan
Tuition reimbursement Company match of charitable contributions
Health & Wellness programs including onsite flu shots and health screenings
Generous time off for vacation and the option to purchase additional vacation days
