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Translational Research Lead at Genmab

Posted in General Business 30+ days ago.

This job brought to you by eQuest

Type: Full-Time
Location: Princeton, New Jersey





Job Description:

Genmab is an international biotechnology company specializing in the invention and development of differentiated human antibody therapeutics for the treatment of cancer and other important human diseases.

About Us:

Genmab is an international biotechnology company specializing in the invention and development of differentiated human antibody therapeutics for the treatment of cancer and other important human diseases.

The team:

You will work in a global multidisciplinary oncology project team to develop novel cancer therapies. As a Translational Research Lead you will drive and contribute to the clinical development of new programs by building and executing the translational research and biomarker strategy.

The Responsibilities:

The Translational Research (TR) lead will be responsible for the translational research and biomarker strategy for the project and will represent the Translational Research group in a multidisciplinary Compound Development Team (CDT).

The TR lead will work independently and in collaboration with other translational research team members to develop an integrated translational/clinical biomarker research strategy and plan including scientific and preclinical justification and rationale for proposed clinical testing, timelines and guidance for operational aspects of the planned translational research strategies. The TR lead will co-chair project-related TR subteam meetings to ensure execution of the translational research and biomarker strategy, review and interpret clinical biomarker data, review new translational research proposals and manage translational aspects of ongoing studies. The TR lead will be responsible for communication of the translational/biomarker project findings and interpretation to the TR leadership and senior managers in Genmab.

The TR lead will enrich translational/biomarker projects in immune-oncology/oncology through interaction with Genmab's Translational Research Department, the New Products Group and the Antibody Research & Technology Group, as well as external leaders.

The TR Lead will:


  • Develop and support the TR/biomarker strategy and workplan for specific Genmab projects, in collaboration with other functional experts, to impact clinical development decision making (i.e.: dose selection using PD markers, patient selection using predictive biomarkers, indication selection based on translational research data, etc.).

  • Oversee the execution of the translational research and biomarker workplan.

  • Communicate TR strategy, plan and findings to CDT, CDT subteams, and governance committees within Genmab.

  • Contribute to the preparation of regulatory documentation and interactions, including preparation of Translational/Biomarker sections in Clinical protocols, Investigator Brochures, Compound Development Plans, and Clinical Study Reports.

  • Establish and maintain collaborative relationships with internal and external functional experts that can contribute to the TR strategy. Responsible for managing scientific content and execution of research agreements with external collaborators.

Your professional profile:


  • A Ph.D. or an M.D./D.V.M./Ph.D. in oncology, preferably immuno-oncology or related field, with at leastfive (5) or more years of translational research, applicable biomarker, and/or drug discovery or clinical trial experience.

  • A strong background in tumor biology and immune-oncology.

  • Experience in pharmaceutical or biotechnology industry research experience desirable.

  • Strong analytical skills and experience working with bioinformaticians to analyze large omics-type datasets

  • A strong publication record demonstrating relevant experience in early drug development, translational research, biomarkers or clinical trials.

  • Strong communication skills and sufficient experience in drug discovery and/or early development to represent a diverse TR and biomarker team in a CDT and to communicate goals and deliverables to senior management and governance committees throughout Genmab.

  • A 'getting things done' mentality, pro-active, enthusiastic and goal orientated.

  • Must be capable of working in global project teams. Travel will be approximately 10-15%.

Dynamic and innovative environment:

Genmab employees work with determination and with respect for each other, consistent with our core values, to achieve our common goals. We give individuals and teams the autonomy to drive development of innovative products and solutions, knowing that integrity is a core value throughout our company. Genmab will offer the successful application a challenging position, where the right candidate will have the opportunity to work with highly specialized people across functions in an informal, multicultural culture, all aiming to make a difference for cancer patients.

Teamwork and respect are central pillars of Genmab's culture and we therefore ensure an inclusive, open, and supportive professional work environment across our international locations. We believe that fostering workplace diversity across social, educational, cultural, national, age and gender lines is a prerequisite for the continued success of the company. We are committed to diversity at all levels of the company and strive to recruit employees with the right skills and competences, regardless of gender, age, ethnicity, etc.

If you would like additional information about this position before applying , please contact our Recruitment Team. Genmab A/S is committed to protecting your personal data and privacy. Through the web site Genmab A/S obtains certain personally identifiable
information provided by you voluntarily.

The personally identifiable information is the information you provide to Genmab A/S when signing up for Genmab A/S's News Alert, Genmab A/S' Event Alert, logging on to Genmab A/S's Investor Portal or mailing to Genmab A/S regarding general or business inquiries or with web site feedback. The personally identifiable information will only be used to provide the services requested by you and to improve our services to you as described in our Privacy
Policies.

Genmab employees work with determination and with respect for each other, consistent with our core values, to achieve our common goals. We give individuals and teams the autonomy to drive development of innovative products and solutions, knowing that integrity is a core value throughout our company. Genmab will offer the successful application a challenging position, where the right candidate will have the opportunity to work with highly specialised people across functions in an informal, multicultural culture, all aiming to make a difference for cancer patients.

Teamwork and respect are central pillars of Genmab's culture and we therefore ensure an inclusive, open, and supportive professional work environment across our international locations. We believe that fostering workplace diversity across social, educational, cultural, national, age and gender lines is a prerequisite for the continued success of the company. We are committed to diversity at all levels of the company and strive to recruit employees with the right skills and competences, regardless of gender, age, ethnicity, etc.

Please note Genmab's policy for all permanently budgeted hires in the Netherlands is to offer a temporary agreement for one year, followed by a temporary employment agreement and a contract for indefinite time after two years of employment regardless of seniority.

If you would like additional information about this position before applying , please contact our Recruitment Team.

Genmab A/S is committed to protecting your personal data and privacy. Through the web site Genmab A/S obtains certain personally identifiable information provided by you voluntarily.
The personally identifiable information is the information you provide to Genmab A/S when signing up for Genmab A/S's News Alert, Genmab A/S' Event Alert, logging on to Genmab A/S's Investor Portal or mailing to Genmab A/S regarding general or business inquiries or with web site feedback. The personally identifiable information will only be used to provide the services requested by you and to improve our services to you as described in our Privacy Policies.





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