Bioinformatics Specialist at Massachusetts General Hospital(MGH)

Posted in Other 12 days ago.

Location: Boston, Massachusetts

Job Description:


The Bioinformatics Specialist I helps to advance computational component of biomedical research at the department and throughout the hospital. Works closely with other investigators to answer key biological questions by performing genome scale computational analyses. The background must demonstrate a proven ability to work collaboratively and perform high quality analyses of large-scale experimental data in a timely manner. Contributes code to shared computational infrastructure and is expected to meet high software development standards. Evaluates existing computational methods and serve as a knowledge resource to collaborators seeking advice about the best tool for a particular problem.

In addition, under the supervision of the Director and with the help of senior members, manages research collaborations, designs Bioinformatics workflows, selects tools and statistical approaches, and executes projects. Demonstrates good understanding of biological problems and in-depth knowledge of computational methods for next-generation sequencing analysis. Demonstrates mature interpersonal skills in communicating with collaborators and driving collaborative research.


    • Provides collaborative advanced Bioinformatics analysis in support for the research projects at the Department of Molecular Biology and Partners in general

    • Drives the Bioinformatics component of the collaborative projects using computation (Linux/Unix environment, Perl, Python, R, or other scripting languages), statistics, good understanding of biological problems, and in-depth knowledge of methods for the analysis of high-throughput biomedical data, with the primary emphasis on next-generation sequencing methods

    • Interprets and translates computational results into biologically relevant conclusions and hypotheses. Discusses biological questions, problems, and outcomes with wet-lab collaborators

    • Addresses scientific ideas and questions of wet-lab collaborators and implements of them in Bioinformatics workflows in real time under the guidance of the Director

    • Clearly and succinctly communicates basic ideas and design of performed computational analyses to biologists and clinicians

    • Works on his/her own Bioinformatics research projects in connection with the Director and senior members



      • Expertise in genomic data analysis - particularly ChIP-seq, RNA-seq, polymorphism discovery, and other NGS methods.

      • Demonstrated understanding of statistics.

      • Expertise working in Unix/Linux environments.

      • Experience with Perl, Python, or other scripting languages.

      • Excellent skills in oral presentation and good writing skills; ability to clearly and succinctly communicate basic ideas of computational analyses to biologists and clinicians.

      • Strong ability and experience in interpreting computational results and translating these results into biologically relevant conclusions and hypotheses.


      • BS in computational biology, bioinformatics, cell biology, or a related field required, MS or PHD strongly preferred.

      • Minimum 2 years of directly related experience expected.

      EEO Statement

      Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. Applications from protected veterans and individuals with disabilities are strongly encouraged.
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