Posted in Other 6 days ago.

Location: Durham, North Carolina

Job Description:

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.


Department of Medicine Division of Nephrology

Job Summary Conduct a variety of investigations in the planning, development and implementation of experimental procedures within the overall scope of a research project at Duke University. Support research activities in a busy, biomedical Nephrology research lab. The ideal candidate will be capable of performing tasks to support a complex research project in a timely, independent and organized manner. Duties Research using vertebrate animals, specifically mice, to study kidney function and cardio vascular functions (30%) Conduct a variety of investigations in the planning, development and implementation of experimental procedures and specialized laboratory techniques in the analyses of in vitro and in vivo models human diseases. Breeding of complex transgenic animals, colony management, animal handling, physiological studies, and sample collections. Collect information and data through observation, experimentation and various other methods, to include operating highly technical laboratory instruments and equipment. Detailed record keeping of animal breeding and generation. Planning and execution of complex, multi-stepped animal studies. Post-operative care of animals.This work will require training for use of animals in research Provide assistance in preparing IACUC protocols and paperwork related to animal research. Research In biomedical laboratory (60%)Proficiency in techniques such as PCR, rt-qPCR, Western blotting, cell culture, ELISAs, gel electrophoresis, preparation and staining of histological specimens. Experience in following and developing experimental protocols is necessary. Advanced knowledge and understanding of biology, molecular biology, chemistry, physiology, and statistics. Experience with micro-arrays, proteomics and metabolomics.

Use of common laboratory equipment such as gel imager, light microscope, plate reader, lab balance, pipettes, centrifuge, autoclave, incubators. Experience in tracking maintenance and upkeep of lab equipment would be beneficial. Adherence to safety and training requirements. Organization of laboratory data, inventory, records. Good organizational skills. Excellent record keeping (electronic lab notebook).Ability to train and supervise other individuals in research techniques. Other professional activities related to research (10%):Experience and comfort with working in teams and possess clear communication skills, both verbal and written. Lab has one PI but several collaborators and the lab environment is open and shared with other investigators Review journals, abstracts and scientific literature to keep abreast of new developments and to obtain information regarding published experimental results to aid in the design and development Scientific writing and communication. There will be regularly-occurring meetings with PI and lab group to review raw data. Applicant will be asked to present data locally or at larger research meetings. Attend and participate in relevant scientific conferences on campus. The ability to critically review scientific literature will be needed. Track record of successful participation in multiple, scientific programs and projects. Effective time management skills. Other general areas to include but not limited to demonstrating integrity in research, possessing a willingness to learn new skills and techniques, and having scientific curiosity and enjoyment in research.

Minimum Qualifications


Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.


Work requires two years of research experience. A related master's OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.