Clinical Development Scientist (Gene Therapy Program) at University of Pennsylvania

Posted in Other 7 days ago.

Location: Philadelphia, Pennsylvania





Job Description:


Job location: Translational Research Laboratories



Employment Type: Full-time
Posted data: 2021-07-14
Req: JR00036121

University Overview
The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn's distinctive interdisciplinary approach to scholarship and learning.Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title
Clinical Development Scientist (Gene Therapy Program)

Job Profile Title
Manager Research Project B

Job Description Summary
The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with the great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.
The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania, has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the "go-to" organization for public and private partners, who want to participate in the gene therapy space. Currently, we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.


Continuation of all GTP positions is contingent upon funding.

Job Description

We are currently seeking a Clinical Development Scientist to support the design of clinical development plans for multiple high-priority programs within the GTP.


Reporting to the Director, Clinical Development, the Clinical Development Scientist will be responsible for the following duties:




  • Under the supervision of the Director, Clinical Development, design clinical development plans for projects under development in the Gene Therapy Program (GTP)




  • Design first in human trials and author clinical study protocol synopses for GTP projects




  • As a member of the GTP research teams, provide clinical and translational input to early discovery projects within GTP to enable IND readiness




  • Design natural history studies in close collaboration with rare disease experts, the preclinical program lead, and the clinical operations lead




  • Provide scientific support to the clinical operations team to develop and execute natural history studies, including but not limited to evaluation of suitable endpoints, vendor capabilities, assay development needs, and case report form (CRF) testing




  • With support from the Director, Clinical Development, may contribute to the evaluation of new research opportunities and potential targets




Other responsibilities may include:




  • Participation in team meetings with industry partners who, as regulatory sponsors, will be accountable for interventional clinical trial execution




  • Contribution to the development of regulatory briefing documents, clinical protocols, and clinical elements of regulatory submission documents




  • Contribution to the organization, conduct of, and participation in Advisory board meetings and orphan disease think tanks






Qualifications:




  • Master's Degree (life sciences or molecular biology desired) and 3 to 5 years of applicable experience or an equivalent combination of education and experience required. Experience with preclinical to clinical translation and bridging into early phase clinical development is preferred.




  • PhD preferred.




  • Demonstrated learning agility.




  • Ability to interact professionally with key leaders, as well as external academic, for-profit, and non-profit organizations.




  • Demonstrated ability to work in teams with people from diverse backgrounds.




  • Ability to work independently and to perform well under pressure and embrace dynamic environment. Strong organizational and time management skills. Excellent oral & written communication skills with exceptional attention to detail.






Job Location - City, State
Philadelphia, Pennsylvania

Department / School
Perelman School of Medicine

Pay Range
$59,703.00 - $113,435.00




Affirmative Action Statement


Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.





Special Requirements


Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.





University Benefits





  • Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family's health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.





  • Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.





  • Retirement: Penn offers generous retirement plans to help you save for your future. Penn's Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.





  • Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family-whatever your personal needs may be.





  • Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you're newly hired, you won't have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.





  • Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That's why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.





  • Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.





  • University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University's libraries and athletic facilities, or visit our arboretum and art galleries. There's always something going on at Penn, whether it's a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you're right in the middle of the excitement-and you and your family can enjoy many of these activities for free.





  • Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.





  • Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.





  • Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.





  • Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.






To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay