Job Description:

Department Description: This position is in Dr. Di Feng's lab in the Division of Nephrology, Department of Medicine. The candidate will work in an established basic science laboratory dedicated to understanding the molecular basis of ACTN4-mediated chronic kidney disease. Representative work has been published in Nature Genetics, Journal of Clinical Investigation, Proceedings of the National Academy of Sciences of the United States of America, and the Journal of the American Society of Nephrology.

The laboratory utilizes a broad range of technologies, including human genetics, cellular assays, and mouse models. We also use innovative techniques involving induced Pluripotent Stem (iPS) cells engineering, organ-on-chips, mass spectrometry, and advanced microscopy. Primary responsibilities of this position include but are not limited to performing experiments for molecular, cellular, and animal studies that characterize kidney disease models. A successful candidate will have a strong interest in learning and applying these techniques toward bettering understanding kidney disease. Prior experience with animal studies is highly valued.

Job Location: Boston, MA

Req ID: 40096BR


Job Summary: The candidate will work in an established basic science laboratory dedicated to understanding the molecular basis of ACTN4-mediated chronic kidney disease. Representative work has been published in Nature Genetics, Journal of Clinical Investigation, Proceedings of the National Academy of Sciences of the United States of America, and the Journal of the American Society of Nephrology. The laboratory utilizes a broad range of technologies, including human genetics, cellular assays, and mouse models. We also use innovative techniques involving induced Pluripotent Stem (iPS) cells engineering, organ-on-chips, mass spectrometry, and advanced microscopy. Primary responsibilities of this position include but are not limited to performing experiments for molecular, cellular, and animal studies that characterize kidney disease models. A successful candidate will have a strong interest in learning and applying these techniques toward bettering understanding kidney disease. Prior experience with animal studies is preferred.

Essential Responsibilities:

1. Conducts routine tests following established procedures, which may include assays, DNA sequencing, tissue culture, protein purification, Western blotting, PCR analysis, electrophoresis, chromatography, etc. (essential)
2. Uses standard research equipment such as microscopes, incubators, autoclaves, centrifuges, etc. (essential)
3. Researches and collects basic study data through monitoring devices and maintains daily logs/basic records of methodologies and test results. With supervision, using databases, may summarize data and interpret results using descriptive statistics and basic hypothesis testing. (essential)
4. Participates in projects that involve rodent animal husbandry breeding and genotyping (essential).
5. May write standard operating procedures for documentation and make informal presentations of these procedures to others in the lab. (essential)
6. Performs literature searches and library investigations as they relate to the research and/or as assigned. (essential)
7. May demonstrate routine laboratory tasks to tests to students and other research personnel. (essential)
8. Maintains own supplies and may be responsible for ordering supplies for the lab. (essential)
9. Due to the dynamic environment in which research exists, must show flexibility in performing principal duties and responsibilities as research projects evolve. (essential)
10. Attends Medical Center lectures regarding all safety requirements/conditions. Attends courses, lectures, and conferences to further own knowledge of research. (essential)

Required Qualifications:

1. Bachelor's degree in Biology, Biochemistry, Life Science or a related scientific field required.


2. 0-1 years related work experience required.


3. Familiarity with basic laboratory instruments and equipment, computers (databases, spreadsheets, statistics) and scientific procedures.


4. Basic familiarity with computers. Ability to navigate at a basic level within web-based applications.

Competencies:

1. 
   Decision Making: Ability to make decisions that are based on specific instructions, standard practices and established procedures which generally require little or no supervision.


2. 
   Problem Solving: Ability to address problems that are routine, somewhat repetitive and generally solved by following clear directions and procedures and by identifying opportunities for process improvements.


3. 
   Independence of Action: Ability to follow general instructions and procedures as provided. Work is monitored by supervisor/manager.


4. 
   Written Communications: Ability to communicate clearly and effectively in written English with internal and external customers.


5. 
   Oral Communications: Ability to understand spoken English in order to follow basic safety instructions and take direction from supervisors; communicate effectively in basic English with patients, families and medical center staff in response to routine questions.


6. 
   Knowledge: Ability to demonstrate basic knowledge of fundamental concepts, practices and procedures with the ability to use them in routine situations. Specialized knowledge not required.


7. 
   Team Work: Ability to interact respectfully with other employees, professional staff and/or external contacts to offer ideas, identify issues, obtain information or deliver services.


8. 
   Customer Service: Ability to demonstrate a positive attitude and respond to requests in a timely and respectful manner.

Physical Nature of the Job:
Light work: Exerting up to 20 pounds of force frequently to move objects. Some elements of the job are sedentary, but the employee will be required to stand for periods of time or move through out the hospital campus Apply Now