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The Sylvester Comprehensive Cancer Center is currently seeking a Assistant Scientist who will join the Cancer Modeling Shared Resource. This translational Facility provides qualified, cost effective and state-of-the art services to foster cancer research advancements and accelerate the discovery of tailored antitumor therapies. We are seeking a dynamic individual who would like to participate in the creation and development of new service lines in a busy and fast-paced environment, mainly focused in the generation, characterization, and analysis of mouse models of disease, including both genetically engineered mice and transplantation-based models. This person will directly assist the Director in running and implementing new services, as well as developing and adapting state-of-the-art technologies to support researchers. He or she will also help supervise the day to day activities of the facility related with these activities. The successful candidate will also develop, implement and update the procedures required to accomplish research goals and preclinical mouse model-related service provision under the direction of Dr. Bilbao.
Specific responsibilities of the position include and are not limited to:
Manage projects involving animal modeling as it collaborates with other team members and relevant parties to handle project intake, define scope, identify deliverables, potential bottlenecks, obstacles, and timelines, ensuring that tasks, priorities, and goals are completed and coordinated with management. This includes designing and performing complex laboratory assignments, as well as planning and conducting experiments related with mouse model generation and characterization, and the generation of novel mouse models of disease.
Manage all aspects of operation in the Modeling area including preparation and maintenance of records and reports, analysis of testing methodologies, training, instrumentation, quality control and compliance. This includes keeping computer records, maintain/update data in computer-based applications/databases (including specialized animal management database), record experimental data, prepare data for analysis, and perform the analysis.
Monitor timelines and track study/project performance, including quality of the work and output, and analyze the successful completion of short- and long-term goals.
Gather usage statistics and other metrics to help assess performance and utilization.
Meet budgetary objectives and adjust project scope, project schedule and project costs based on project constraints and financial analysis.
Develop service fees. Prepare online request form and materials for brochures and reports, as required by the study/project.
Review documents to generate reports, including the implementation and use of a laboratory information system.
Reviews data collected, inserts into the study/project database, and prepares data for analysis. Act as a liaison to researchers to establish, develop and perform animal protocols using advanced scientific techniques, while being able to work independently and to solve technical and scientific problems.
Supervise, train staff and users. Work with the director to develop, adapt and implement new services and state-of-the-art technologies to address scientific problems.
Take charge of lab equipment bookings, animal transfers, IACUC protocols, radioactive licenses and reagent and equipment inventories, as required. Ensure equipment is operated and maintained according to manufacturer's instructions, ensure supplies are adequate for the work to be performed. Develop training schedules, including conducting training seminars, image analysis, and data management, as appropriate.
Educate users on the values and limitations of animal modeling and provide input on appropriate study protocols. Coordinate with relevant stakeholders, vendors and other organizations for instrument installations, basic use, issue diagnosis, and repair.
Design and implement equipment maintenance schedules, software license structures, and regular software updates for relevant hardware and software. Maintain accurate records for quality control, quality assurance and research data.
Develop and implement a quality control system. Maintain cutting-edge knowledge of the animal modeling field including major advances and emerging trends. Manage email communications and maintain internal documentation. Adhere to University and unit-level policies and procedures; safeguard University assets; participate in University/outside educational training as required. Perform other duties as requested.
Qualified candidates must possess a PhD degree in Animal science, Biology, Biological Sciences, Life Science and/or other related field, or equivalent experience. Any appropriate combination of relevant education, experience and/or certifications may be considered.
The successful candidate must have a minimum of three years of animal research experience performing the routine as well as the specialized technical procedures mentioned above, preferably supervising people and assisting in the day to day management of a research laboratory. Extensive knowledge of Standard Operating Procedures for animal facilities, understanding the requirements for maintaining (immunocompromised) laboratory animals, together with excellent computer skills and proficiency with Microsoft Office and animal/record management databases is required. Experience with analytical techniques (PCR, hematology and clinical chemistry analyzer, histology, flow cytometry, noninvasive imaging) is preferred.
Knowledge, Skills and Attitudes:
Proactively helpful in all aspects of the job, whether it involves communication, training, reporting, or project management.
Mechanical ability and dexterity when performing the different lab and animal-related techniques.
Ability to understand preclinical science.
Skill in completing assignments accurately and with attention to detail.
Ability to observe, assess, and record animal symptoms, reactions, and progress.
Ability to understand and follow specific instructions and procedures.
Excellent computer skills and proficiency with general and specialized data analysis software and databases is required.
Knowledge of the use and maintenance of laboratory facilities and/or equipment.
Knowledge of animal husbandry requirements, methods, and techniques, including the ability to establish dosages and administer drugs to animals, and to maintain laboratory/veterinary/animal husbandry records.
Extensive knowledge of Standard Operating Procedures for animal facilities, understanding the requirements for maintaining (immunocompromised) laboratory animals, including knowledge of local, state, and federal regulations pertaining to animal husbandry.
Knowledge of sterile procedures, general laboratory operations and/or procedures, as well as knowledge of supplies, equipment, and/or services ordering and inventory control.
Self-motivated individual with a strong desire to learn.
Exceptional critical thinking and strong analytical, problem solving, and troubleshooting skills.
Excellent organizational skills.
Excellent interpersonal and communication skills. He or she is expected to interact with a variety of staff (facility team, users, and other related facilities) in a professional, polite, and positive attitude.
Ability to supervise and manage people.
Excellent English (both verbal and written) required.
Ability to shift focus between multiple projects, organize and prioritize work under pressure while meeting deadlines.
Excellent time-management skills.
Ability to work evenings, nights, and weekends as necessary.
Commitment to the University's core values.
Ability to work independently and in a collaborative environment.
Ability to work in an interdisciplinary team under the direction of the Director of the Facility.
Ability to perform other duties as assigned.
The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.
UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.
Patient safety is a top priority. As a result, during the Influenza ("the flu") season (September through April), the University Of Miami Miller School Of Medicine requires all employees who provide ongoing services to patients, work in a location (all Hospitals and clinics) where patient care is provided, or work in patient care or clinical care areas, to have an annual influenza vaccination. Failure to meet this requirement will result in rescinding or termination of employment.
The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information.