Posted in Other 12 days ago.
Location: Miami, Florida
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About This Position
Join a vibrant research program in the laboratory of Dr. J. William Harbour in the Sylvester Comprehensive Cancer Center, Bascom Palmer Eye Institute, and Interdisciplinary Stem Cell Institute at the University of Miami. This position will predominantly involve bioinformatic and computational research associated with a variety of established and new next-generation sequencing approaches in the study of eye cancers and developmental stem cell models.
My lab employs next-generation sequencing approaches, including bulk DNA and RNA sequencing, single-cell RNA and DNA sequencing, spatial transcriptomics, ChIP-seq, ATAC-seq, and Hi-C to study primary and metastatic tumors, blood and other body fluids, induced pluripotent stem cells, and developmental animal models. We applied the 10x Genomics single-cell sequencing platform to uveal melanoma resulting in a new investigator initiated clinical trial ( Nat Commun 2020;11:496) and in human olfactory neuroepithelium, where we discovered a new neuronal stem cell ( Nat Neurosci . 2020;23:323-326), which contributed to the discovery of how SARS-CoV-2 infects the olfactory epithelium to cause anosmia. We strive to push beyond standard pipelines, and have created numerous in-house bioinformatic tools, including SparK (https://github.com/harbourlab/SparK), UPhyloPlot2 (https://github.com/harbourlab/UPhyloPlot), and PieParty (https://github.com/harbourlab/PieParty).
The successful candidate will have: (1) a recent PhD or MD in a related field of study, (2) proficiency in R, Python, and Linux shell scripting, and (3) evidence of stage-appropriate research productivity. The Postdoc will perform bioinformatics, computational, and scientific research under the supervision of Dr. J. William Harbour. The Postdoc will implement, maintain, and execute pipelines for genetic, genomic and phenotypic feature analysis. Skills in developing advanced analytical models are highly desired. The candidate should have the capability to perform analysis and assessments of technical approaches and systems to provide solutions to support strategic decisions in the Harbour Lab, which employs a collaborative team science approach. Skill in collecting, organizing, and analyzing data, and solve a variety of computational and/or scientific problems are expected. There will be ample opportunities for developing individual research projects and building skills in scientific writing. Skill in collecting, organizing, and analyzing data. Ability to recognize, analyze, and solve a variety of problems. Ability to exercise sound judgment in making critical decisions.
The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.
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