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In Vitro Toxicologist at Altria

Posted in Other 30+ days ago.

Location: Richmond, Virginia





Job Description:


In Vitro Toxicologist

Job Locations

US-VA-Richmond

Requisition ID

2021-3705


















Operating Company
Altria Client Services
Category
Legal & Regulatory Affairs - Regulatory Affairs
Position Type
Full-Time
Relocation Benefits Eligible
Yes

Overview

Have a degree in Toxicology or related field with experience in conducting or supervising in vitro cytotoxicity and genotoxicity studies? If so, we invite you to be a part of Altria's 10-year Harm Reduction vision and journey to responsibly lead the transition of adult smokers to a non-combustible future.


We are hiring an In Vitro Toxicologist to join our Biological Sciences Insights (BSI) group in Richmond, VA. or we are open to remote work arrangements. The selected candidate will use their scientific and technical expertise to design, implement, and report toxicological outcomes from preclinical (in vitro) studies to aid in regulatory submission, product development and foundational research.


Specific accountabilities include:
* Subject matter expertise in preclinical (in vitro) testing of test materials (individual and mixtures; tobacco and nicotine products), under the applicable principles of Good Laboratory Practices (GLP) and 3Rs, in support of overall risk assessment
* Serve as Sponsor Representative, planning, monitoring, and managing studies conducted at external Contract Research Organizations (CROs)
o Key tasks: prepare Statement of Work, review proposals, oversee study related budget, finalize study design/protocols, and monitor deliverables to completion (to reporting and archiving)
* Identify forward-looking in vitro capability gaps; screen and qualify candidate external CROs
* May require occasional travel (10-20%) to CRO site for lab selection, inspection, or study monitoring
* Preclinical lead for regulatory toxicology testing; scope, communicate findings, and write preclinical sections of regulatory dossiers; peer-reviewed publication
* Attend and/or present at scientific meetings to represent company's work or to augment job skills.
* Monitor emerging Tox21 assessment tools (e.g., in vitro- and in silico-based) for its relevance in screening materials or products; communicate with external and internal partners as part of foundational research


Qualifications include:
* Bachelors or preferably an advanced degree (MSc or PhD) in toxicology, pharmacology, biochemistry or related field; DABT is a plus
* Five or more years of hands-on experience in conducting regulatory (e.g., OECD) in vitro genotoxicity and cytotoxicity studies (Three or more years of experience will be acceptable for candidates with advanced degrees).
* Comprehensive understanding of Data Integrity and GLP; working knowledge of quality assurance inspection process at CROs (as study director or study monitor)
* Excellent project scoping and management skills; attention to detail and ability to meet deliverables under a highly dynamic environment
* Excellent written and oral communication skills; Strong interpersonal and problem-solving skills; work effectively both independently and as a team
* Additional hands-on experiences with primary cells and organotypic tissues or organs; conducting mechanistic toxicity studies; high-content or high-throughput screening assays (e.g., Tox 21) and air-liquid-interface in vitro testing, as a plus.

In addition, we offer an excellent compensation package including a competitive base salary, comprehensive health/vision/dental insurance, participation in our deferred profit sharing and incentive compensation programs as well as a relocation assistance package.

Company Overview

Altria Group is a FORTUNE 200 company that leads the premier tobacco companies in the United States. Headquartered in Richmond, Virginia, Altria Group holds diversified positions across tobacco, alcohol, and cannabis. Our tobacco companies include some of the most enduring names in American business: Philip Morris USA, U.S. Smokeless Tobacco Company, John Middleton. We have 35 percent ownership of JUUL Labs, Inc., the nation's leading e-vapor company. And we have an 80 percent interest in Helix Innovations, which manufactures and markets on!, an oral tobacco-derived nicotine pouch product. We complement our total tobacco business with our ownership of Ste. Michelle Wine Estates and our significant equity investment in Anheuser-Busch InBev, the world's largest brewer. Altria's significant stake in Cronos Group, a leading global cannabinoid company, represents an exciting new global growth opportunity.

At Altria, we celebrate the power of diverse teams working together to shape our future. We are inspired to bring our best because our unique strengths are valued. We believe our personal success and progress should be guided by Our Cultural Aspiration, a new articulation of what we value and who we aspire to be, collectively. Our Cultural Aspiration respects and complements individual identity, embracing each other's unique strengths, welcoming newcomers and developing the best, most inclusive and diverse teams. Over the next 10 years, we have the opportunity to make more progress on harm reduction than we have in the past 50 years. Join us as we work together to shape a better future for adult tobacco consumers, our employees, and our shareholders. Each Altria company is an equal opportunity employer.


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