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Investigator I (Formulation & Delivery / Nanoparticle) at Seqirus

Posted in Other 30+ days ago.

Type: Full Time
Location: Cambridge, Massachusetts





Job Description:

Come join a company that tackles fascinating problems and find solutions to complex challenges. With deep expertise in influenza science, our team works on cutting-edge research, pioneering technologies to optimise the manufacturing process and improve the effectiveness of influenza vaccines. We operate as one integrated global organisation, drawing together expert staff from different countries to collaborate. Together, we are working on the front line to protect communities from seasonal influenza and global pandemic threats. When you join Seqirus, you join a team dedicated to making a difference in people's lives. It's a feeling of possibility, creativity, and purpose that inspires us every day.
Job Summary:
This Investigator is a responsible for development and performance of mRNA vaccine and adjuvanted protein vaccine formulation and delivery technology, to support vaccine discovery and development.
Major Responsibilities:
mRNA vaccine formulation and delivery development
- Development of delivery technology eg. Lipid nanoparticle, for efficient and safe delivery of mRNA vaccine.
- Development of mRNA vaccine formulation to improve vaccine stability.

Vaccine formulation to support vaccine development
- Development and performance of mRNA vaccine formulation, biophysical characterization and stability evaluation to support vaccine process development.
- Performance of mRNA vaccine and adjuvanted protein vaccine formulation to support vaccine preclinical development in animal models.

Documentation and presentation of scientific results
- Write experimental protocols and prepare internal reports. Maintain lab notebooks.
- Present research project progress within and beyond Research.
- Lead technical advancements and publications.
- Interact with cross-functional project teams and stakeholders as key contact.
- Interact with external collaborators as key contact.

Lab management
- Maintain functional laboratory equipment and follow HSE regulation.
Minimum Requirements:
- Ph.D. in Pharmaceutical Science, Chemistry, Biomedical engineering, Biochemistry or a related field
- 0-3 year academic or pharmaceutical/biotech experience in biologics formulation and delivery
- Strong knowledge and experience with nanoparticle fabrication and characterization is required.
- Strong knowledge and experience with medicinal chemistry especially lipid chemistry is required.
- Knowledge and experience with mRNA molecular biology and biochemistry are desired.
- Creative and the ability to generate accurate and reproducible results along with multi-tasking and working effectively in a fast-paced environment are critical.
- Strong organizational, written and oral communication skills and ability to work in teams is essential..

Seqirus is an Equal Opportunity Employer


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