Process Development Senior Scientist at Amgen

Posted in Science 29 days ago.

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Location: Cambridge, Massachusetts





Job Description:

Amgen

Job ID: R-91948
Location: Cambridge, MA, US 02139

Amgen's Attribute Sciences (AS) department within the Process Development (PD) organization defines the favorable quality characteristics of the therapies it produces, and optimizes state-of-the-art analytical tools to guide that development. The Pivotal PD organizations focus is developing and commercializing robust manufacturing processes across a wide range of therapeutic modalities, including (but not limited to) monoclonal and bispecific antibodies, bispecific T-cell engagers ("BiTEs"), live modalities, and synthetic medicines.

There an exciting new career opportunity to join the Pivotal Attribute Sciences team based in Amgen Cambridge, Massachusetts site. In this role you will support development of late stage development protein products including:

Interfacing and collaborating with other functional areas in matrix environment, serving as analytical subject matter expert to support and advise design of characterization studies, data analysis and investigations

Leveraging latest advances in protein analytics to develop, optimize, troubleshoot, remediate, qualify, validate and transfer analytical methods

Design and execution of analytical studies to support process and product characterization for late stage development products utilizing protein chemistry, separation sciences and mass spectrometry

Interpreting results, authoring technical protocols, reports, analytical method descriptions and analytical CMC sections in regulatory documents

Leading program-oriented Attribute Sciences matrix analytical team and ensuring that project deliverables are appropriately planned, executed and communicated to cross-functional partners

Supervising or mentoring junior staff

Basic Qualifications:

Doctorate degree and 2 years of scientific experience

OR

Master's degree and 5 years of scientific experience

OR

Bachelor's degree and 7 years of scientific experience

Preferred Qualifications:

PhD in Biochemistry or related field

8+ years' experience in industrial analytical laboratories supporting method development and testing of commercial or clinical protein products

Advanced expertise in liquid chromatography, protein chemistry and mass spectrometry of protein molecules, including glycoproteins, experience in LC and LC-MS method development and qualification

Knowledge of methods for higher order structure characterization of proteins

Proficiency in solving complex problems, ability to work independently, proactively seek outside resources and collaborate, self-starter and team player with strong leadership and decision making skills capable of providing guidance to junior staff

Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on complex projects

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

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